fda.gov/food/guidanceregulation/guidancedocumentsregulatoryinformation/ucm072997.htm Guidance for industry: Final rule declaring dietary supplements containing ephedrine alkaloids adulterated because they present an unreasonable risk small entity compliance guide.drugs-supplements/ephedra-ma-huang/background/hrb-20059270 Mechanism, efficacy, and safety of an ephedrine, caffeine, and aspirin combination in the treatment of obesity. ods.od.nih.gov/factsheets/EphedraandEphedrine-HealthProfessional/ Ephedra and ephedrine alkaloids for weight loss and athletic performance.ods.od.nih.gov/Health_Information/Ephedra.aspx
Cardiovascular toxicities of performance-enhancing substances in sports. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Long-term use of aspirin, even in small doses, has been associated with an increased risk of bleeding in the gastrointestinal tract. In other words, its helps maintain the stimulation effects that the caffeine and ephedrine help provide. When taken as part of an ECA stack, aspirin prevents norepinephrine levels from decreasing. Caffeine consumption can increase feelings of alertness, effectively reducing fatigue.īut when taken in large doses, caffeine can also cause:Īspirin is a pain reliever. It’s commonly found in coffee, tea, and soft drinks. CaffeineĬaffeine is also a stimulant of both the CNS and the cardiovascular system. This makes it an important part of the fight-or-flight response during times of high stress.Įphedra also raises heart rate and can also cause constriction of blood vessels, leading to high blood pressure. Norepinephrine is used to get the body ready for action and activity. This extract stimulates the central nervous system (CNS) through release of a compound called norepinephrine.
It’s been used in traditional Chinese medicine for centuries and is also referred to as “ma huang.” Ephedrine is derived from the Ephedra plant.
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